Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709308 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1GAAFFAR1 | |
| SCHEMBL7701376 | 1.00 | TSHR (0.41) | TSHRALDH1A1TDP1GAAFFAR1 | |
| SCHEMBL7706303 | 0.98 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1GAAFFAR1 | |
| SCHEMBL7701340 | 0.94 | ALDH1A1 (0.41) | TSHRALDH1A1GAATHRB | |
| SCHEMBL28232252 | 0.93 | TSHR (0.53) | TSHR | |
| SCHEMBL19019776 | 0.93 | CYP4F2 (0.42) | TSHRALDH1A1TDP1GAAFFAR1 | |
| SCHEMBL28769247 | 0.93 | TSHR (0.53) | TSHR | |
| SCHEMBL10447459 | 0.93 | TSHR (0.53) | TSHR | |
| SCHEMBL5856021 | 0.90 | TSHR (0.50) | TSHRALDH1A1THRB | |
| SCHEMBL19019798 | 0.90 | CYP4F2 (0.40) | TSHRALDH1A1TDP1GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355702-B1 | HEAT DECOMPOSITION OF ACRYLIC RESIN; CURING; CROSSLINKED NETWORK | CORNELL RESEARCH FOUNDATION, INC. | 2002-03-12 | — | — | US | disclosed |