SCHEMBL10447459

SCHEMBL10447459

C=C(C)C(=O)OC(C)(C)CCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CES2 O00748 3/20 0.38
GGPS1 O95749 5/20 0.36
SMPD1 P17405 1/20 0.36
FDPS P14324 7/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28769247 1.00 TSHR (0.53) TSHRMEN1MAPTKMT2AATM
SCHEMBL28232252 1.00 TSHR (0.53) TSHRMEN1MAPTKMT2AATM
SCHEMBL5856021 0.98 TSHR (0.50) TSHRMEN1MAPTKMT2AATM
SCHEMBL703086 0.93 TSHR (0.47) TSHRMEN1MAPTKMT2AATM
SCHEMBL7709308 0.93 TSHR (0.41) TSHR
SCHEMBL7706289 0.93 TSHR (0.41) TSHR
SCHEMBL7701376 0.93 TSHR (0.41) TSHR
SCHEMBL19085379 0.91 TSHR (0.49) TSHRMEN1MAPTKMT2AATM
SCHEMBL7706303 0.91 ALDH1A1 (0.41) TSHR
SCHEMBL27857234 0.87 TSHR (0.55) TSHRMEN1MAPTKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267708-B1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INT LTD (GB) 2025-07-02 EP disclosed
US-12281203-B2 Thermally responsive brush polymers having a copolymer backbone and copolymer arms INFINEUM INTERNATIONAL LIMITED (GB) 2025-04-22 US disclosed
US-20240309155-A1 Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms INFINEUM INTERNATIONAL LIMITED (GB) 2024-09-19 US disclosed
EP-4267708-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS Infineum International Limited (GB) 2023-11-01 EP disclosed
CN-116981758-A Thermally responsive brush polymers having a copolymer backbone and copolymer arms 英菲诺姆国际有限公司 2023-10-31 CN disclosed
WO-2022136384-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-30 WO disclosed
EP-0363928-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-18 EP disclosed