Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.46 |
| ▸ | FNTB | P49356 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706347 | 1.00 | FNTA (0.46) | FNTAFNTBCYP3A4CYP2C19AGTR2 | |
| SCHEMBL8212186 | 0.87 | FNTA (0.44) | FNTAFNTBAGTR2 | |
| SCHEMBL8212192 | 0.87 | FNTA (0.44) | FNTAFNTBAGTR2 | |
| SCHEMBL8198535 | 0.86 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL8205645 | 0.86 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL8206498 | 0.83 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL8227503 | 0.81 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL8227501 | 0.81 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL7706180 | 0.81 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL7706173 | 0.81 | FNTA (0.51) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | claimed |
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | claimed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | claimed |
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |