Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.62 |
| ▸ | BCL6 | P41182 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707100 | 0.91 | TACR1 (0.64) | TACR1 | |
| SCHEMBL6016683 | 0.89 | TACR1 (0.49) | TACR1BCL6CETPGPBAR1 | |
| SCHEMBL6016463 | 0.81 | TACR1 (0.49) | TACR1BCL6 | |
| SCHEMBL6016505 | 0.81 | TACR1 (0.48) | TACR1BCL6CETP | |
| SCHEMBL6016483 | 0.81 | TACR1 (0.48) | TACR1BCL6 | |
| SCHEMBL6016533 | 0.80 | TACR1 (0.48) | TACR1 | |
| SCHEMBL6016693 | 0.79 | TACR1 (0.49) | TACR1 | |
| SCHEMBL4111165 | 0.79 | BCL6 (0.47) | BCL6 | |
| SCHEMBL4111167 | 0.79 | BCL6 (0.47) | BCL6 | |
| SCHEMBL7704079 | 0.77 | TACR1 (0.69) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000073279-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-07 | — | — | WO | disclosed |