Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | BCL6 | P41182 | 3/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016683 | 0.92 | TACR1 (0.49) | TACR1BCL6 | |
| SCHEMBL6016463 | 0.92 | TACR1 (0.49) | TACR1BCL6 | |
| SCHEMBL6016505 | 0.91 | TACR1 (0.48) | TACR1BCL6 | |
| SCHEMBL6016533 | 0.90 | TACR1 (0.48) | TACR1 | |
| SCHEMBL6016604 | 0.88 | TACR1 (0.53) | TACR1TACR3 | |
| SCHEMBL6016586 | 0.87 | TACR1 (0.64) | TACR1 | |
| SCHEMBL6016479 | 0.86 | TACR1 (0.53) | TACR1 | |
| SCHEMBL6016693 | 0.86 | TACR1 (0.49) | TACR1 | |
| SCHEMBL7706672 | 0.81 | TACR1 (0.62) | TACR1BCL6 | |
| SCHEMBL7707100 | 0.79 | TACR1 (0.64) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-B1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-02-08 | — | — | EP | claimed |