Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706672 | 0.91 | TACR1 (0.62) | TACR1 | |
| SCHEMBL6016463 | 0.88 | TACR1 (0.49) | TACR1 | |
| SCHEMBL6016683 | 0.80 | TACR1 (0.49) | TACR1 | |
| SCHEMBL6016505 | 0.79 | TACR1 (0.48) | TACR1 | |
| SCHEMBL6016483 | 0.79 | TACR1 (0.48) | TACR1 | |
| SCHEMBL6016533 | 0.79 | TACR1 (0.48) | TACR1 | |
| SCHEMBL7704079 | 0.78 | TACR1 (0.69) | TACR1 | |
| SCHEMBL7709573 | 0.78 | TACR1 (0.55) | TACR1 | |
| SCHEMBL4126105 | 0.78 | PTPN11 (0.43) | — | |
| SCHEMBL4126108 | 0.78 | PTPN11 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000073279-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-07 | — | — | WO | disclosed |