Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248930 | 0.91 | ALDH1A1 (0.39) | ALDH1A1LMNASLC15A2PTPN1NPC1 | |
| SCHEMBL26553932 | 0.84 | PAOX (0.41) | ALDH1A1LMNASLC15A2ACHEPAOX | |
| SCHEMBL2578186 | 0.77 | LMNA (0.40) | ALDH1A1LMNASLC15A2ACHEKMT2A | |
| SCHEMBL24694384 | 0.76 | TDP1 (0.39) | TDP1 | |
| SCHEMBL3102816 | 0.75 | — | — | |
| SCHEMBL27836278 | 0.75 | TSHR (0.36) | ALDH1A1 | |
| SCHEMBL30510726 | 0.75 | TSHR (0.50) | ALDH1A1LMNAKMT2A | |
| SCHEMBL23529489 | 0.75 | GLP1R (0.31) | — | |
| SCHEMBL27969681 | 0.74 | CHRM2 (0.44) | ALDH1A1LMNAPTPN1NPC1RAB9A | |
| SCHEMBL4989248 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |