Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706731 | 0.99 | CYP1B1 (0.45) | CYP1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7703698 | 0.90 | CYP1B1 (0.41) | CYP1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7703947 | 0.87 | MEN1 (0.39) | CYP1B1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7703674 | 0.86 | MEN1 (0.41) | CYP1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7703835 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL7709619 | 0.85 | MEN1 (0.39) | CYP1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7709683 | 0.84 | PRMT1 (0.41) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL7706689 | 0.84 | MEN1 (0.39) | CYP1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7712190 | 0.82 | MEN1 (0.60) | CYP1B1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL8465317 | 0.81 | KMT2A (0.44) | CYP1B1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |