Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703835 | 0.99 | ALDH1A1 (0.42) | PRMT1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL7709615 | 0.92 | HTR1A (0.40) | PRMT1MAPTKMT2AHTR1AMEN1 | |
| SCHEMBL7709336 | 0.91 | CYP1A2 (0.46) | ALDH1A1MAPTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8465317 | 0.90 | KMT2A (0.44) | PRMT1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL7703674 | 0.85 | MEN1 (0.41) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL7706731 | 0.85 | CYP1B1 (0.45) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL7706752 | 0.84 | CYP1B1 (0.44) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL7706689 | 0.83 | MEN1 (0.39) | ALDH1A1MAPTHTTLMNAMAPK1 | |
| SCHEMBL7706791 | 0.82 | PRMT1 (0.60) | PRMT1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL7709619 | 0.82 | MEN1 (0.39) | ALDH1A1MAPTHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |