Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706732 | 0.81 | NAMPT (0.37) | NAMPTALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL7706728 | 0.77 | NAMPT (0.41) | NAMPTALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL12748885 | 0.73 | NPC1 (0.47) | NAMPTALDH1A1SMN1; SMN2MYCTSHR | |
| SCHEMBL9336190 | 0.68 | NAMPT (0.45) | NAMPTALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL7712512 | 0.68 | NAMPT (0.35) | NAMPT | |
| SCHEMBL13946795 | 0.67 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL784551 | 0.67 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL8002346 | 0.67 | HPGD (0.50) | ALDH1A1MAPTPOLBSMN1; SMN2HTT | |
| SCHEMBL1663159 | 0.67 | NAMPT (0.44) | NAMPTALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL11488582 | 0.66 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |