Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706913 | 0.81 | NAMPT (0.38) | NAMPTKDM4EMEN1POLBMAPT | |
| SCHEMBL7706728 | 0.81 | NAMPT (0.41) | NAMPTKDM4EMEN1POLBMAPT | |
| SCHEMBL1663159 | 0.74 | NAMPT (0.44) | NAMPTKDM4EMEN1POLBMAPT | |
| SCHEMBL9336190 | 0.72 | NAMPT (0.45) | NAMPTKDM4EMEN1POLBMAPT | |
| SCHEMBL7712512 | 0.71 | NAMPT (0.35) | NAMPT | |
| SCHEMBL12748885 | 0.66 | NPC1 (0.47) | NAMPTKDM4ETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13851546 | 0.66 | NAMPT (0.41) | NAMPTKDM4EMEN1POLBMAPT | |
| SCHEMBL6735445 | 0.66 | TP53 (0.53) | RECQLALDH1A1 | |
| SCHEMBL8531872 | 0.65 | LMNA (0.51) | KDM4EMAPTKMT2ATDP1HSD17B10 | |
| SCHEMBL6403050 | 0.65 | LMNA (0.51) | KDM4EMAPTKMT2ATDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |