SCHEMBL7707153

SCHEMBL7707153

Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1S(C)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA2 P47869 4/20 0.49
GABRB2 P47870 4/20 0.49
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA4 P48169 1/20 0.43
GABRE P78334 1/20 0.43
GABRA6 Q16445 1/20 0.43
GABRG1 Q8N1C3 1/20 0.43
GABRG3 Q99928 1/20 0.43
GABRQ Q9UN88 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7713025 0.86 GABRA2 (0.49) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL6055712 0.85 GABRA2 (0.48) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL6055885 0.85 GABRA2 (0.48) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL7711437 0.85 GABRA2 (0.48) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL6055741 0.82 GABRA2 (0.45) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL7711193 0.82 GABRA2 (0.45) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL6055644 0.81 GABRA2 (0.44) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL7713312 0.79 GABRA2 (0.48) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL6978060 0.77 GABRA2 (0.50) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL9780177 0.77 GABRA2 (0.50) GABRA2GABRB2GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5916618-A PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT RHONE-POULENC AGRICULTURE LTD. (GB) 1999-06-29 US claimed
US-6372774-B1 THESE COMPOUNDS POSSESS ARTHROPODICIDAL, PLANT NEMATOCIDAL, ANTHELMINTIC AND ANTI-PROTOZOAL PROPERTIES RHONE-POULENC AGRICULTURE LTD. (GB) 2002-04-16 US disclosed
US-5916618-A PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT RHONE-POULENC AGRICULTURE LTD. (GB) 1999-06-29 US disclosed
US-5714191-A PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT RHONE-POULENC AGRICULTURE LTD. (GB) 1998-02-03 US disclosed
US-5608077-A INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS RHONE-POULENC AGRICULTURE LTD. (GB) 1997-03-04 US disclosed
US-5547974-A INSECTICIDES, NEMATOCIDES, ANTHELMINTICS RHONE-POULENC AGRICULTURE LTD. (GB) 1996-08-20 US disclosed
CN-1025811-C Pesticidal method using N-phenyl pyrazoles MAY & BAKER LTD (GB) 1994-09-07 CN disclosed
EP-0579280-A1 Pesticidal method using N-phenylpyrazoles RHONE-POULENC AGROCHIMIE (FR) 1994-01-19 EP disclosed
US-5232940-A Controlling insects, plant nematodes, helminths, protozoa BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) 1993-08-03 US disclosed
EP-0234119-A1 Pesticidal method using N-phenylpyrazoles RHONE-POULENC AGROCHIMIE (FR) 1987-09-02 EP disclosed
CN-86108643-A Insecticidal method using N-phenylpyrazoles 1987-07-29 CN disclosed
WO-1987003781-A1 PESTICIDAL METHOD USING N-PHENYLPYRAZOLES MAY & BAKER LIMITED (GB) 1987-07-02 WO disclosed