Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975907 | 0.83 | GABRA2 (0.48) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL6974567 | 0.82 | MEN1 (0.39) | — | |
| SCHEMBL9780177 | 0.82 | GABRA2 (0.50) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7815528 | 0.78 | GABRA2 (0.47) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL6055869 | 0.78 | GABRA2 (0.47) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL6555658 | 0.78 | GABRA2 (0.46) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7707153 | 0.77 | GABRA2 (0.49) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7805791 | 0.76 | GABRA2 (0.45) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL9780190 | 0.76 | GABRA2 (0.45) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL10348128 | 0.76 | CYP3A4 (0.48) | GABRA2GABRB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159298-C | Parasiticidal compound | ������ҩ������˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1106386-C | Parasiticidal pyrazoles | PFIZER LTD (US) | 2003-04-23 | — | — | CN | disclosed |
| EP-0946515-B1 | PARASITICIDAL PYRAZOLES | PFIZER LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| EP-0871617-B1 | PARASITICIDAL COMPOUNDS | PFIZER (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6268509-B1 | PESTICIDES | PFIZER INC | 2001-07-31 | — | — | US | disclosed |
| US-6255333-B1 | HUMANS OR ANIMALS | PFIZER INC. | 2001-07-03 | — | — | US | disclosed |
| US-6075043-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-06-13 | — | — | US | disclosed |
| CN-1192735-A | Parasiticidal compounds | FRIZER INC (US) | 1998-09-09 | — | — | CN | disclosed |