Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.72 |
| ▸ | MMP3 | P08254 | 12/20 | 0.72 |
| ▸ | MMP9 | P14780 | 5/20 | 0.72 |
| ▸ | MMP14 | P50281 | 5/20 | 0.72 |
| ▸ | MMP13 | P45452 | 3/20 | 0.72 |
| ▸ | MMP1 | P03956 | 3/20 | 0.69 |
| ▸ | BMP1 | P13497 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706922 | 0.92 | MMP2 (0.85) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7109428 | 0.91 | MMP2 (0.82) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7707403 | 0.89 | MMP2 (0.69) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6449140 | 0.83 | MMP2 (1.00) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7704488 | 0.82 | MMP2 (0.79) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6435957 | 0.81 | MMP2 (1.00) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7108052 | 0.80 | MMP2 (0.79) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6137316 | 0.78 | MMP2 (0.53) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL6137313 | 0.78 | MMP2 (0.53) | MMP2MMP3MMP9MMP14MMP13 | |
| SCHEMBL7108964 | 0.77 | MMP2 (0.71) | MMP2MMP3MMP9MMP14MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350907-B1 | PEPTIDE ENZYME INHIBITORS | PFIZER INC | 2002-02-26 | — | — | US | disclosed |