Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Hydroxy-2-Butoxybenzene SCHEMBL543533 | 0.94 | LMNA (0.69) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL462067 | 0.89 | LMNA (0.67) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL1834630 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL22207331 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL9048074 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL1836622 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL270163 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL22207144 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL1834963 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 | |
| SCHEMBL6276541 | 0.87 | LMNA (0.64) | LMNAMAPTGAAJAK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362124-B1 | INCLUDING ORGANOSILICON COMPOUND IN A COORDINATION CATALYST WHICH ALSO CONTAINS; ORGANOMAGNESIUM, ORGANOALUMINUM AND TITANIUM COMPOUNDS; SUPERIOR POLYMERIZATION ACTIVITY AND STEREOSPECIFIC EFFICIENCY. | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-03-26 | — | — | US | disclosed |