SCHEMBL7707415

SCHEMBL7707415

O=C(Cl)c1ccc(Cl)c(C(=O)Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
DPP4 P27487 1/20 0.40
ALOX15 P16050 1/20 0.35
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
TSHR P16473 3/20 0.34
TP53 P04637 1/20 0.34
CASP1 P29466 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MAPK1 P28482 2/20 0.31
HIF1A Q16665 1/20 0.31
CYP3A4 P08684 1/20 0.31
TTR P02766 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18301265 0.87 ALDH1A1 (0.50) ALDH1A1DPP4ALOX15KDM4EHSD17B10
SCHEMBL1313390 0.83 ALDH1A1 (0.61) ALDH1A1DPP4KDM4EHSD17B10KMT2A
SCHEMBL9197919 0.82 ALDH1A1 (0.48) ALDH1A1DPP4ALOX15KDM4EHSD17B10
SCHEMBL967909 0.81 CYP3A4 (0.44) ALDH1A1DPP4ALOX15KDM4EKMT2A
SCHEMBL7172627 0.81 ABL1 (0.45) ALDH1A1KDM4EHSD17B10KMT2AATM
SCHEMBL7463501 0.81 CA12 (0.41) ALDH1A1KDM4EHSD17B10KMT2ATSHR
SCHEMBL103521 0.80 ALDH1A1 (0.44) ALDH1A1ALOX15KDM4EKMT2AATM
SCHEMBL18298919 0.77 ALDH1A1 (0.40) ALDH1A1DPP4KDM4EHSD17B10KMT2A
SCHEMBL106507 0.76 HPGD (0.44) ALDH1A1ALOX15KDM4EKMT2AATM
SCHEMBL10625935 0.76 ALDH1A1 (0.37) ALDH1A1ALOX15KMT2AATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6346310-B1 MAGNETIC LAYER ON FLEXIBLE SUPPORT AND BACKCOAT LAYER ON SURFACE FUJI PHOTO FILM CO., LTD. (JP) 2002-02-12 US disclosed
EP-1049076-A1 MAGNETIC RECORDING MEDIUM FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-0664014-B1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL NV (NL) 1998-08-19 EP disclosed
EP-0243652-B1 SYNTHESIS OF HIGH PURITY 5-CHLOROISOPHTHALOYL CHLORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1990-10-03 EP disclosed
US-4776986-A CATALYTIC CHLORINATION OF ISOPHTHALOYL CHLORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1988-10-11 US disclosed
EP-0243652-A1 Synthesis of high purity 5-chloroisophthaloyl chloride OCCIDENTAL CHEMICAL CORPORATION (US) 1987-11-04 EP disclosed
US-4001179-A Bis-(tetrahalophthalimidocarbonyl)-benzene VELSICOL CHEMICAL CORPORATION (US) 1977-01-04 US disclosed