SCHEMBL103521

SCHEMBL103521

O=C(Cl)c1ccc(C(=O)Cl)c(Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.44
▸ ALOX15 P16050 2/20 0.44
▸ TSHR P16473 3/20 0.37
▸ CASP1 P29466 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP1A2 P05177 1/20 0.36
▸ CES2 O00748 2/20 0.36
▸ CES1 P23141 2/20 0.36
▸ MAOB P27338 1/20 0.35
▸ KMT2A Q03164 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL967909 0.89 CYP3A4 (0.44) ALDH1A1ALOX15TSHRCASP1SMN1; SMN2
SCHEMBL28124327 0.87 MAPK1 (0.48) ALDH1A1ALOX15TSHRCES2KMT2A
SCHEMBL9812941 0.86 ALDH1A1 (0.39) ALDH1A1ALOX15TSHRCASP1SMN1; SMN2
SCHEMBL27867898 0.85 ALDH1A1 (0.35) ALDH1A1ALOX15TSHRCASP1SMN1; SMN2
SCHEMBL107481 0.85 CLCN2 (0.38) ALDH1A1ALOX15TSHRMAPTCYP1A2
SCHEMBL110164 0.85 ALDH1A1 (0.50) ALDH1A1ALOX15TSHRCASP1SMN1; SMN2
SCHEMBL27459872 0.85 ALDH1A1 (0.39) ALDH1A1ALOX15TSHRCASP1KDM4E
Hydrochloric Acid SCHEMBL11884093 0.83 ALDH1A1 (0.38) ALDH1A1ALOX15TSHRCASP1KDM4E
SCHEMBL5285030 0.82 ALDH1A1 (0.52) ALDH1A1ALOX15TSHRSMN1; SMN2KDM4E
SCHEMBL28842145 0.82 SELL (0.48) ALDH1A1ALOX15MAPTKMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1035395-C Fibers with improved hydrolytic stability DU PONT (US) 1997-07-09 — — CN claimed
EP-0397160-B1 Process for making fibers with improved hydrolytic stability DU PONT (US) 1996-07-10 — — EP claimed
US-5037596-A Aromatic polyamide containing chloroterephthaloyl chloride E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-06 — — US claimed
US-5003036-A Tensile strength E. I. DU PONT DE NEMOURS 1991-03-26 — — US claimed
CN-1047350-A Fiber with hydrolytic stability of improvement DU PONT (US) 1990-11-28 — — CN claimed
EP-0397160-A2 Process vor making fibers with improved hydrolytic stability E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-14 — — EP claimed
JP-2258741-A — — None — — JP disclosed
CN-119744222-A Fire-resistant composite sheet 杜邦安全与建筑公司 2025-04-01 — — CN disclosed
US-12252815-B2 Cut resistant ply-twisted yarns and fabrics made thereof DUPONT SAFETY & CONSTRUCTION, INC. (US) 2025-03-18 — — US disclosed
CN-119654233-A Fire-resistant composite sheet 杜邦安全与建筑公司 2025-03-18 — — CN disclosed
EP-4193016-B1 PAPER COMPRISING ARAMID PULP SUITABLE FOR ELECTROCHEMICAL CELLS, AND ELECTROCHEMICAL CELLS MADE THEREFROM DUPONT SAFETY & CONSTRUCTION INC (US) 2024-07-17 — — EP disclosed
CN-118302576-A Nonwoven sheet comprising a substrate and an applied fibril cover 杜邦安全与建筑公司 2024-07-05 — — CN disclosed
CN-118201769-A Ballistic resistant material made from mechanically entangled woven fabrics free of non-woven fibers and method of making same 杜邦安全与建筑公司 2024-06-14 — — CN disclosed
EP-0378366-A1 Preparation of 2-chloroterephthaloyl chloride E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-07-18 — — EP disclosed
US-4507467-A IMPACT STRENGTH TEIJIN LIMITED (JP) 1985-03-26 — — US disclosed
US-4507465-A IMPACT STRENGTH TORAY INDUSTRIES, INC. (JP) 1985-03-26 — — US disclosed
EP-0045934-B1 WHOLLY AROMATIC POLYAMIDE FIBER AND FILM AND PROCESS FOR PREPARATION THEREOF TEIJIN LIMITED (JP) 1984-12-05 — — EP disclosed
EP-0113252-A2 Process for producing block copolyamide TORAY INDUSTRIES, INC. (JP) 1984-07-11 — — EP disclosed
US-4342862-A Polyesters of trans-1,4-cyclohexanedicarboxylic acid and 2-phenylhydroquinone and modifications thereof EASTMAN KODAK COMPANY (US) 1982-08-03 — — US disclosed
EP-0045934-A1 Wholly aromatic polyamide fiber and film and process for preparation thereof TEIJIN LIMITED (JP) 1982-02-17 — — EP disclosed
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