Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707607 | 1.00 | USP2 (0.38) | USP2KDM4EALDH1A1OPRM1OPRD1 | |
| SCHEMBL7707606 | 1.00 | USP2 (0.38) | USP2KDM4EALDH1A1OPRM1OPRD1 | |
| SCHEMBL7708096 | 0.81 | CHRNB2 (0.40) | ALDH1A1TSHR | |
| SCHEMBL7708094 | 0.81 | CHRNB2 (0.40) | ALDH1A1TSHR | |
| SCHEMBL7710789 | 0.81 | CHRNB2 (0.40) | ALDH1A1TSHR | |
| SCHEMBL12497513 | 0.81 | USP2 (0.41) | USP2KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7704824 | 0.79 | CHRNB2 (0.43) | ALDH1A1TSHRHTT | |
| SCHEMBL7704822 | 0.79 | CHRNB2 (0.43) | ALDH1A1TSHRHTT | |
| SCHEMBL7708146 | 0.79 | CHRNB2 (0.43) | ALDH1A1TSHRHTT | |
| SCHEMBL17625024 | 0.78 | KDM4E (0.45) | USP2KDM4EALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359174-B1 | REACTING ALLYL REACTANT WITH ACID CHLORIDE IN PRESENCE OF LEWIS ACID CATALYST | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-03-19 | — | — | US | disclosed |