Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708096 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4CARM1 | |
| SCHEMBL7708094 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4CARM1 | |
| SCHEMBL7704824 | 0.98 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4CARM1 | |
| SCHEMBL7704822 | 0.98 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4CARM1 | |
| SCHEMBL7708146 | 0.98 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4CARM1 | |
| SCHEMBL25993302 | 0.87 | KMT2A (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4KMT2A | |
| SCHEMBL7707610 | 0.81 | USP2 (0.38) | ALDH1A1TSHR | |
| SCHEMBL7706868 | 0.81 | MEN1 (0.35) | KMT2ALMNAMEN1ALDH1A1SIGMAR1 | |
| SCHEMBL7707606 | 0.81 | USP2 (0.38) | ALDH1A1TSHR | |
| SCHEMBL7710812 | 0.81 | MEN1 (0.35) | KMT2ALMNAMEN1ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359174-B1 | REACTING ALLYL REACTANT WITH ACID CHLORIDE IN PRESENCE OF LEWIS ACID CATALYST | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-03-19 | — | — | US | disclosed |