SCHEMBL7707612

SCHEMBL7707612

O=C(O)C(=O)c1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC9A1 P19634 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
LMNA P02545 1/20 0.32
GRIK1 P39086 1/20 0.32
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32
GRIA4 P48058 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRIK3 Q13003 1/20 0.32
GRIN2B Q13224 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30660771 1.00 TDP1 (0.34) TDP1KEAP1NFE2L2ALDH1A1MAPK1
SCHEMBL827009 0.83 TDP1 (0.45) TDP1KEAP1NFE2L2ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL9310900 0.81 TDP1 (0.44) TDP1KEAP1NFE2L2ALDH1A1MAPK1
Potassium SCHEMBL9658910 0.81 TDP1 (0.44) TDP1KEAP1NFE2L2ALDH1A1MAPK1
SCHEMBL11675795 0.81 TDP1 (0.44) TDP1KEAP1NFE2L2ALDH1A1MAPK1
SCHEMBL9310884 0.78 SLC9A1 (0.34) TDP1KEAP1NFE2L2ALDH1A1MAPK1
SCHEMBL3235898 0.75 CA1 (0.34) TDP1SLC9A1MEN1KMT2A
Water SCHEMBL9659734 0.73 HIPK2 (0.33) SLC9A1
SCHEMBL9310891 0.73 KMT2A (0.33) TDP1ALDH1A1MAPK1SLC9A1MEN1
SCHEMBL28287874 0.72 NPSR1 (0.50) TDP1ALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116744792-A Liquid agrochemical composition 诺力昂化学品国际有限公司 2023-09-12 CN disclosed
CN-103960281-A Mixture for controlling undesired vegetation selected from prosopis and acacia DU PONT 2014-08-06 CN disclosed
CN-102118967-B Method for controlling undesired mimosoideae plants DU PONT 2014-04-02 CN disclosed
US-RE37664-E1 Use of derivatives of N-phenl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs BASF AKTIENGESSELLSCHAFT (DE) 2002-04-16 US disclosed
US-5045105-A Use of derivatives of n-phenyl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs BASF AKTIENGESELLSCHAFT (DE) 1991-09-03 US disclosed
US-4999041-A DEFOLIANTS, COTTON FARMING BASF AKTIENGESELLSCHAFT (DE) 1991-03-12 US disclosed