SCHEMBL827009

SCHEMBL827009

O=C(O)c1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPK1 P28482 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
LMNA P02545 1/20 0.41
GRIK1 P39086 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIK2 Q13002 1/20 0.41
GRIK3 Q13003 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL9658910 0.98 TDP1 (0.44) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL11675795 0.98 TDP1 (0.44) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
Hydrochloric Acid SCHEMBL9310900 0.98 TDP1 (0.44) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL30660771 0.83 TDP1 (0.34) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL7707612 0.83 TDP1 (0.34) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL9310884 0.82 SLC9A1 (0.34) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL13771182 0.81 ALDH1A1 (0.48) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL7587086 0.81 KEAP1 (0.48) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL7584014 0.81 TDP1 (0.41) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1
SCHEMBL30050749 0.81 TDP1 (0.50) TDP1ALDH1A1SMN1; SMN2MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104988531-B The method that a kind of selective dechlorination of chloro-pyridine formic acid electro-catalysis prepares pyridine carboxylic acid 浙江工业大学 2017-11-07 CN claimed
CN-105461622-A Method for preparing 4-amino-3,6-dichloropicolinic acid by reducing 4-amino-3,5,6-trichloropicolinic acid SHANDONG VICOME LUNAN PESTICIDE CO LTD 2016-04-06 CN claimed
CN-104988531-A Method for preparing picolinic acid through electro-catalysis selective dechloridation of chloropicolinicacid UNIV ZHEJIANG TECHNOLOGY 2015-10-21 CN claimed
EP-0254982-B1 ELECTROLYTIC CELL WITH NICKEL ALLOY ANODES FOR ELECTROCHEMICAL DECHLORINATION DOWELANCO (US) 1991-10-30 EP claimed
EP-0252520-B1 PROCESS FOR SILVER CATHODE ACTIVATION DOWELANCO (US) 1991-09-18 EP claimed
US-4778576-A PREFERENTIAL HYDROGEN REPLACEMENT BY ELECTROLYSIS; ANODE ALLOY SURFACE OF NICKEL, CHROMIUM AND MOLYBDENUM; CORROSION RESISTANCE THE DOW CHEMICAL COMPANY (US) 1988-10-18 US claimed
US-4755266-A Process for silver cathode activation THE DOW CHEMICAL COMPANY (US) 1988-07-05 US claimed
EP-0164430-B1 EXPANDED METAL SILVER CATHODE FOR ELECTROLYTIC REDUCTION OF POLYCHLOROPICOLINATE ANIONS THE DOW CHEMICAL COMPANY (US) 1988-04-06 EP claimed
EP-0254982-A2 Electrolytic cell with nickel alloy anodes for electrochemical dechlorination DOWELANCO (US) 1988-02-03 EP claimed
EP-0252520-A1 Process for silver cathode activation DOWELANCO (US) 1988-01-13 EP claimed
EP-0164430-A1 Expanded metal silver cathode for electrolytic reduction of polychloropicolinate anions THE DOW CHEMICAL COMPANY (US) 1985-12-18 EP claimed
US-4460441-A Expanded metal as more efficient form of silver cathode for electrolytic reduction of polychloropicolinate anions THE DOW CHEMICAL COMPANY (US) 1984-07-17 US claimed
EP-0023077-B1 ELECTROLYTIC PRODUCTION OF CERTAIN TRICHLOROPICOLINIC ACIDS AND/OR 3,6-DICHLOROPICOLINIC ACID THE DOW CHEMICAL COMPANY (US) 1984-06-20 EP claimed
EP-0023077-A2 Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1981-01-28 EP claimed
US-4217185-A Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1980-08-12 US claimed
US-3971799-A Preparation of 3,5,6-trichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1976-07-27 US claimed
US-12624005-B2 Synthesis of 4-amino-6-(heterocyclic)picolinates CORTEVA AGRISCIENCE LLC (US) 2026-05-12 US disclosed
CN-119710765-B Powder electrode for electrochemical reduction dechlorination of chloropicolinic acid and preparation and application thereof 浙江工业大学 2025-05-27 CN disclosed
US-3971799-A Preparation of 3,5,6-trichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1976-07-27 US disclosed
US-3971799-A Preparation of 3,5,6-trichloropicolinic acid THE DOW CHEMICAL COMPANY (US) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624005-B2 Synthesis of 4-amino-6-(heterocyclic)picolinates CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS TDP1 3832/4885ALDH1A1 843/4885SMN1; SMN2 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.