Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 11/20 | 0.67 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.67 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.67 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886459 | 0.94 | MAPK10 (0.70) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL2881183 | 0.83 | MAPK10 (0.76) | MAPK10MAPK9MAPK8LCKPIK3CA | |
| SCHEMBL4022971 | 0.83 | MAPK10 (0.84) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL21067982 | 0.80 | MAPK10 (1.00) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL186278 | 0.80 | MAPK10 (1.00) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL29432586 | 0.80 | MAPK10 (1.00) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| Acetonitrile SCHEMBL7707016 | 0.80 | MAPK10 (0.66) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL4020500 | 0.80 | MAPK10 (0.73) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL4022963 | 0.79 | MAPK10 (0.84) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| Acetonitrile SCHEMBL7701908 | 0.79 | MAPK10 (0.66) | MAPK10MAPK9MAPK8MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | disclosed |