Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 12/20 | 1.00 |
| ▸ | MAPK9 | P45984 | 11/20 | 1.00 |
| ▸ | MAPK8 | P45983 | 3/20 | 1.00 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186278 | 1.00 | MAPK10 (1.00) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL29432586 | 1.00 | MAPK10 (1.00) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL4022963 | 0.92 | MAPK10 (0.84) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL4022971 | 0.91 | MAPK10 (0.84) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL2887536 | 0.86 | MAPK10 (0.76) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL2884761 | 0.86 | MAPK10 (0.75) | MAPK10MAPK9MAPK8MKNK1MKNK2 | |
| SCHEMBL2881373 | 0.86 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL2879038 | 0.86 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL4023159 | 0.86 | MAPK10 (0.75) | MAPK10MAPK9MAPK8NPC1RAB9A | |
| SCHEMBL2886187 | 0.86 | MAPK10 (0.75) | MAPK10MAPK9MAPK8MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220061311-A1 | COMPOSITIONS AND METHODS FOR REDUCING CRYOPRESERVATION TOXICITY | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2022-03-03 | — | — | US | claimed |
| US-20220061311-A1 | COMPOSITIONS AND METHODS FOR REDUCING CRYOPRESERVATION TOXICITY | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2022-03-03 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220061311-A1 | COMPOSITIONS AND METHODS FOR REDUCING CRYOPRESERVATION TOXICITY | IQGAP1, UGGT1, FLNA | MAPK10 748/4885MAPK9 288/4885MAPK8 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.