Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.44 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746936 | 1.00 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL1156355 | 1.00 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL19607964 | 0.92 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL5143910 | 0.89 | MEN1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL23168896 | 0.88 | MEN1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ANAAA | |
| SCHEMBL8046166 | 0.88 | NAAA (0.70) | MEN1KMT2ANAAACASP2EPHX1 | |
| SCHEMBL10357569 | 0.88 | NAAA (0.70) | MEN1KMT2ANAAACASP2EPHX1 | |
| SCHEMBL20472580 | 0.88 | NAAA (0.70) | MEN1KMT2ANAAACASP2EPHX1 | |
| SCHEMBL20472253 | 0.88 | NAAA (0.70) | MEN1KMT2ANAAACASP2EPHX1 | |
| SCHEMBL8879613 | 0.88 | NAAA (0.70) | MEN1KMT2ANAAACASP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365172-B1 | SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE | BIOAMIDE, INC. | 2002-04-02 | — | — | US | claimed |
| US-6120788-A | Bioabsorbable triglycolic acid poly(ester-amide)s | BIOAMIDE, INC. (US) | 2000-09-19 | — | — | US | claimed |
| US-20130035402-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-07 | — | — | US | disclosed |
| US-8309132-B2 | Bioabsorbable polyesteramides and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2012-11-13 | — | — | US | disclosed |
| US-8309132-B2 | Bioabsorbable polyesteramides and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2012-11-13 | — | — | US | disclosed |
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2009-11-19 | — | — | US | disclosed |
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2009-11-19 | — | — | US | disclosed |
| US-6365172-B1 | SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE | BIOAMIDE, INC. | 2002-04-02 | — | — | US | disclosed |
| US-6120788-A | Bioabsorbable triglycolic acid poly(ester-amide)s | BIOAMIDE, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0621881-B1 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) | MINNESOTA MINING & MFG (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0621881-A1 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES). | MINNESOTA MINING & MFG (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5286837-A | Suspending in an amide solvent | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| WO-1993015130-A2 | PROCESS FOR INCREASING STABILITY OF POLY(ESTERAMIDES) | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285896-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | PAICS, UROD, PUF60 | ALDH1A1 3434/4885SMN1; SMN2 1627/4885MEN1 162/4885 |
| US-20130035402-A1 | BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF | PAICS, UROD, PUF60 | ALDH1A1 3434/4885SMN1; SMN2 1627/4885MEN1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.