SCHEMBL7707730

SCHEMBL7707730

Cc1c[c]cc(C)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
AKT2 P31751 2/20 0.39
BRD4 O60885 2/20 0.39
CHEK1 O14757 1/20 0.39
BRD2 P25440 1/20 0.39
ALDH1A1 P00352 1/20 0.38
PTGS1 P23219 2/20 0.38
PTGS2 P35354 2/20 0.38
CYP2A6 P11509 1/20 0.37
CYP2B6 P20813 1/20 0.37
ACHE P22303 3/20 0.36
TSHR P16473 2/20 0.36
TDO2 P48775 1/20 0.36
KMT2A Q03164 1/20 0.36
ALOX12 P18054 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ESR2 Q92731 1/20 0.34
PDE4A P27815 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17180550 0.95 ALDH1A1 (0.41) MAPTLMNAHTTAKT2BRD4
SCHEMBL11285380 0.87 CYP2A6 (0.41) MAPTLMNAHTTAKT2BRD4
SCHEMBL28387274 0.82 APP (0.44) MAPTLMNAALDH1A1KMT2A
SCHEMBL6941941 0.80 ACHE (0.40) ALDH1A1PTGS2CYP2A6ACHEHSD17B10
SCHEMBL12816033 0.78 MAPT (0.34) MAPTLMNAHTTAKT2BRD4
SCHEMBL9784280 0.76 ACHE (0.40) ALDH1A1PTGS1PTGS2ACHE
SCHEMBL4426820 0.76 TSHR (0.50) MAPTLMNAHTTAKT2BRD4
SCHEMBL7460316 0.75 CYP2A6 (0.42) MAPTLMNAHTTALDH1A1PTGS1
SCHEMBL9349953 0.75 MAPT (0.36) MAPTLMNAHTTAKT2BRD4
SCHEMBL20873646 0.74 MAPT (0.43) MAPTLMNAHTTAKT2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4035360-A TISSUE SPECIFICITY, CRYSTALLINE PFIZER INC. (US) 1977-07-12 US claimed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
EP-4342883-A1 PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT Tosoh Corporation (JP) 2024-03-27 EP disclosed
CN-117440940-A Material for photoelectric conversion element for image pickup element and photoelectric conversion element for image pickup element 东曹株式会社 2024-01-23 CN disclosed
CN-110997648-B Condensed ring compound 东曹株式会社 2023-12-19 CN disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
EP-4198163-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN Tosoh Corporation (JP) 2023-06-21 EP disclosed
CN-116157382-A Material for metal patterning, amine compound, electronic device, and method for forming metal pattern 东曹株式会社 2023-05-23 CN disclosed
WO-2023013697-A1 MATERIAL FOR METAL PATTERNING, FLUORO COMPOUND, THIN FILM FOR METAL PATTERNING, ORGANIC ELECTROLUMINESCENCE DEVICE, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN 東ソー株式会社 2023-02-09 WO disclosed
WO-2023013615-A1 AMINE COMPOUND, HOLE INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2023-02-09 WO disclosed
EP-2902391-B1 NOVEL AMINE COMPOUND AND USE THEREOF TOSOH CORP (JP) 2017-03-08 EP disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-20150243901-A1 NOVEL AMINE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2015-08-27 US disclosed
EP-2902391-A1 NOVEL AMINE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2015-08-05 EP disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP disclosed
CN-104011022-A 4-aminocarbazole compound and use of same TOSOH CORP 2014-08-27 CN disclosed
CN-101677577-A Pesticidal composition and method for controlling a pest SUMITOMO CHEMICAL CO 2010-03-24 CN disclosed
EP-1242399-A1 $g(a)-ARYLETHYLPIPERAZINE DERIVATIVES AS NEUROKININ ANTAGONISTS UCB S.A. (BE) 2002-09-25 EP disclosed
WO-2001046167-A1 α-ARYLETHYLPIPERAZINE DERIVATIVES AS NEUROKININ ANTAGONISTS UCB, S.A. (BE) 2001-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243901-A1 NOVEL AMINE COMPOUND AND USE THEREOF DRD1, MLLT1, DRD4 MAPT 2447/4885LMNA 3891/4885HTT 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.