Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.76 |
| ▸ | FNTB | P49356 | 13/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181649 | 0.90 | FNTA (0.67) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL5733786 | 0.87 | FNTA (1.00) | FNTAFNTBCYP3A4 | |
| SCHEMBL13186537 | 0.87 | FNTA (1.00) | FNTAFNTBCYP3A4 | |
| SCHEMBL7762145 | 0.84 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL6010264 | 0.84 | FNTA (0.78) | FNTAFNTBCYP3A4 | |
| SCHEMBL6010160 | 0.84 | FNTA (0.78) | FNTAFNTBCYP3A4 | |
| SCHEMBL3847890 | 0.83 | FNTA (0.76) | FNTAFNTBCYP3A4 | |
| SCHEMBL11954827 | 0.81 | FNTA (0.82) | FNTAFNTBCYP3A4PGGT1B | |
| SCHEMBL6587313 | 0.81 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL3436599 | 0.80 | FNTA (0.81) | FNTAFNTBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365600-B1 | FOR THERAPY OF CONDITION ASSOCIATED WITH SMOOTH MUSCLE CELL PROLIFERATION IN A WARM-BLOODED ANIMAL WHICH COMPRISES ADMINISTERING IMIDAZOL-5-YL-METHYL-2-QUINOLINONE DERIVATIVES | JANSSEN PHARMACEUTICA, N.V. | 2002-04-02 | — | — | US | disclosed |