Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125062 | 0.89 | LCK (0.43) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL84322 | 0.86 | LCK (0.44) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL16309121 | 0.81 | ING2 (0.45) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL2884819 | 0.80 | CA1 (0.42) | ALDH1A1CASP6MEN1KMT2ATSHR | |
| SCHEMBL9337835 | 0.79 | LCK (0.36) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL17039274 | 0.79 | NT5E (0.46) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL9337500 | 0.79 | ALDH1A1 (0.49) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL9337495 | 0.79 | LCK (0.36) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL6931230 | 0.79 | ENPP2 (0.41) | LCKFYNING2ALDH1A1CYP2C9 | |
| SCHEMBL15139587 | 0.78 | CA1 (0.37) | ALDH1A1CYP2C9CYP2C19CASP6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140329746-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2014-11-06 | — | — | US | disclosed |
| US-8835654-B2 | Method and compositions for treating amyloid-related diseases | BHI LIMITED PARTNERSHIP (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20140107027-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BHI LIMITED PARTNERSHIP (CA) | 2014-04-17 | — | — | US | disclosed |
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| US-6355711-B1 | KETONE ESTER AS PLASTICIZER | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-03-12 | — | — | US | disclosed |
| EP-0680463-B2 | PROCESS FOR THE PRODUCTION OF PLASTICIZER AND POLYOL ESTERS | EXXONMOBIL CHEM PATENTS INC (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-1073622-A1 | HIGH PERFORMANCE PLASTICIZERS FROM BRANCHED OXO ALCOHOLS | EXXON CHEMICAL PATENTS INC. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054277-A1 | HIGH PERFORMANCE PLASTICIZERS FROM BRANCHED OXO ALCOHOLS | EXXON CHEMICAL PATENTS INC. (US) | 1999-10-28 | — | — | WO | disclosed |
| EP-0680463-B1 | PROCESS FOR THE PRODUCTION OF PLASTICIZER AND POLYOL ESTERS | EXXON CHEMICAL PATENTS INC (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0787120-A1 | PREPARATION OF PLASTICIZER ESTERS FROM PHTHALIC ANHYDRIDE RESIDUE | EXXON CHEMICAL PATENTS INC. (US) | 1997-08-06 | — | — | EP | disclosed |
| US-5534652-A | Preparation of plasticizer esters from phthalic anhydride residue | EXXON CHEMICAL PATENTS INC. (ECPI) (US) | 1996-07-09 | — | — | US | disclosed |
| US-5532405-A | MONITORING CONCENTRATION OF LOWER BOILING ALCOHOL SO THAT MORE MAY BE ADDED TO MAINTAIN PREDETERMINED CONCENTRATION | EXXON CHEMICAL PATENTS INC. (US) | 1996-07-02 | — | — | US | disclosed |
| WO-1996011903-A1 | PREPARATION OF PLASTICIZER ESTERS FROM PHTHALIC ANHYDRIDE RESIDUE | EXXON CHEMICAL PATENTS INC. (US) | 1996-04-25 | — | — | WO | disclosed |
| WO-1996002489-A1 | PREPARATION OF ESTERS BY THE STAGED ADDITION OF THE LOWER BOILING POINT COMPONENT OF MIXED ALCOHOLS OR ACIDS | EXXON CHEMICAL PATENTS INC. (US) | 1996-02-01 | — | — | WO | disclosed |
| WO-1995029888-A1 | PREPARATION OF PLASTICIZER OR POLYOL ESTERS BY THE STAGED ADDITION OF THE LOWER BOILING POINT REACTANT | EXXON CHEMICAL PATENTS INC. (US) | 1995-11-09 | — | — | WO | disclosed |
| US-5324853-A | Continuous mixing and removal of water during esterification | EXXON CHEMICAL PATENTS INC. (US) | 1994-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329746-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | APP, PSEN1, PSEN2 | LCK 4148/4885FYN 1370/4885ING2 3810/4885 |
| US-20140107027-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | APP, PSEN1, PSEN2 | LCK 4148/4885FYN 1370/4885ING2 3810/4885 |
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | APP, PSEN1, PSEN2 | LCK 4428/4885FYN 1474/4885ING2 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.