Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 17/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416292 | 0.91 | S1PR3 (0.46) | S1PR3ALDH1A1MAPTTSHR | |
| SCHEMBL7425401 | 0.87 | MAPT (0.43) | S1PR3ALDH1A1MAPTTSHR | |
| SCHEMBL7466262 | 0.85 | S1PR3 (0.41) | S1PR3ALDH1A1MAPTTSHRSLC22A12 | |
| SCHEMBL7428559 | 0.85 | TP53 (0.50) | S1PR3MAPT | |
| SCHEMBL7424404 | 0.85 | S1PR3 (0.42) | S1PR3ALDH1A1MAPT | |
| SCHEMBL7422342 | 0.84 | S1PR3 (0.42) | S1PR3ALDH1A1MAPTTSHR | |
| SCHEMBL7468201 | 0.84 | MEN1 (0.43) | S1PR3MAPTTSHR | |
| SCHEMBL7470080 | 0.84 | S1PR3 (0.41) | S1PR3MAPT | |
| SCHEMBL7420331 | 0.84 | S1PR3 (0.41) | S1PR3MAPT | |
| SCHEMBL7425649 | 0.83 | MAPT (0.47) | S1PR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358992-B1 | Method of inhibiting neoplastic cells with indole derivatives | CELL PATHWAYS, INC. | 2002-03-19 | — | — | US | disclosed |