Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.44 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046796 | 0.98 | ADRA2A (0.55) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL28046706 | 0.98 | ADRA2A (0.55) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL28046710 | 0.98 | ADRA2A (0.55) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| Piperazine SCHEMBL4470404 | 0.91 | ADRA2A (0.49) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL21067687 | 0.86 | ADRA2A (0.63) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL14629679 | 0.79 | ADRA2A (0.56) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL5851701 | 0.79 | ADRA2A (0.56) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL1842264 | 0.79 | ADRA2A (0.56) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL708660 | 0.78 | ADRA2A (0.56) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL17213665 | 0.77 | KDM4E (0.56) | ADRA2AADRA2CADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821585-B1 | USE OF ALPHA 1L-AGONISTS IN THE TREATMENT OF URINARY INCONTINENCE | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-01-10 | — | — | EP | claimed |
| EP-1285653-A1 | Use of alpha-1L agonists in the treatment of incontinence | Boehringer Ingelheim Pharma KG (DE) | 2003-02-26 | — | — | EP | claimed |
| JP-3379960-B2 | — | — | 2003-02-24 | — | — | JP | claimed |
| EP-0821585-A1 | USE OF $g(a) 1L? AGONISTS IN THE TREATMENT OF INCONTINENCE | BOEHRINGER INGELHEIM KG (DE) | 1998-02-04 | — | — | EP | claimed |
| WO-1996032939-A1 | USE OF α1L AGONISTS IN THE TREATMENT OF INCONTINENCE | BOEHRINGER INGELHEIM KG (DE) | 1996-10-24 | — | — | WO | claimed |
| EP-0538262-A1 | N-DIMETHOXY PHENYL ALKYL-N'-IMIDAZOLYL PHENYL AMIDINE DERIVATIVES AND PROCESS THEREOF | IL YANG PHARM. CO., LTD. (KR) | 1993-04-28 | — | — | EP | claimed |
| WO-1992000966-A1 | N-DIMETHOXY PHENYL ALKYL-N'-IMIDAZOLYL PHENYL AMIDINE DERIVATIVES AND PROCESS THEREOF | IL YANG PHARM. CO., LTD. (KR) | 1992-01-23 | — | — | WO | claimed |
| EP-0013252-B1 | CARDIAC RHYTHM REDUCTION AGENT | C.H. BOEHRINGER SOHN (DE) | 1987-09-23 | — | — | EP | claimed |
| EP-0029505-B1 | SUBSTITUTED PHENYLAMINO-2-IMIDAZOLINE-2 DERIVATIVES, THEIR ACID ADDITION SALTS, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | C.H. BOEHRINGER SOHN (DE) | 1984-09-12 | — | — | EP | claimed |
| EP-0030620-B1 | SUBSTITUTED 2-PHENYLAMINO-2-IMIDAZOLINES, ACID ADDITION SALTS THEREOF, MEDICAMENTS CONTAINING THEM AND PROCESS FOR PREPARING THEM | C.H. BOEHRINGER SOHN (DE) | 1984-06-13 | — | — | EP | claimed |
| EP-0007986-B1 | SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINES-(2), THEIR ACID ADDITION SALTS, MEDICAMENTS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | C.H. BOEHRINGER SOHN (DE) | 1981-09-16 | — | — | EP | claimed |
| EP-0031429-A1 | 2-(N-(2-Fluoro-6-bromophenyl)-N-(thiemyl-2-methyl)-amino)-2-imidazoline, its addition salts, pharmaceutical compositions containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1981-07-08 | — | — | EP | claimed |
| EP-0030620-A2 | Substituted 2-phenylamino-2-imidazolines, acid addition salts thereof, medicaments containing them and process for preparing them | C.H. BOEHRINGER SOHN (DE) | 1981-06-24 | — | — | EP | claimed |
| EP-0030616-A1 | Substituted 2-phenylamino-2-imidazolines, their acid addition salts, medicaments containing them and processes for preparing same | C.H. BOEHRINGER SOHN (DE) | 1981-06-24 | — | — | EP | claimed |
| EP-0029505-A1 | Substituted phenylamino-2-imidazoline-2 derivatives, their acid addition salts, medicaments containing them and process for their preparation | C.H. BOEHRINGER SOHN (DE) | 1981-06-03 | — | — | EP | claimed |
| EP-0007991-A1 | Substituted 2-phenylamino-imidazolines-(2), their acid addition salts, medicaments containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1980-02-20 | — | — | EP | claimed |
| EP-0007406-A1 | Substituted 2-phenylamino-imidazolines-(2), their acid addition salts, medicaments containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1980-02-06 | — | — | EP | claimed |
| EP-0007422-A1 | Substituted 2-phenylamino-imidazolines-(2), their acid addition salts, medicaments containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1980-02-06 | — | — | EP | claimed |
| EP-0007428-A1 | Substituted 2-phenylamino-imidazolines-(2), their acid addition salts, medicaments containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1980-02-06 | — | — | EP | claimed |
| EP-0007438-A1 | Substituted 2-phenylamino-2-imidazolines, their acid addition salts, pharmaceutical compositions containing them and process for their preparation | C.H. BOEHRINGER SOHN (DE) | 1980-02-06 | — | — | EP | claimed |