Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 18/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 18/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 18/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7707903 | 1.00 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7702078 | 0.88 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7702079 | 0.88 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7707363 | 0.85 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BCCRL2CCR2 | |
| SCHEMBL7707365 | 0.85 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BCCRL2CCR2 | |
| Hydrochloric Acid SCHEMBL7082192 | 0.84 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7707909 | 0.83 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7707913 | 0.83 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7702081 | 0.79 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL7702084 | 0.79 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358959-B1 | FOR THERAPY OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2002-03-19 | — | — | US | claimed |
| US-6358959-B1 | FOR THERAPY OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2002-03-19 | — | — | US | disclosed |