Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706678 | 1.00 | KDM6B (0.46) | KDM6BMAOAMAOBDPP4RIPK1 | |
| SCHEMBL7230282 | 0.84 | KDM6B (0.61) | KDM6BMAOAMAOBDPP4RIPK1 | |
| SCHEMBL7711037 | 0.84 | KDM6B (0.61) | KDM6BMAOAMAOBDPP4RIPK1 | |
| SCHEMBL370923 | 0.82 | DPP4 (0.45) | KDM6BMAOAMAOBDPP4RIPK1 | |
| SCHEMBL10078140 | 0.82 | DPP4 (0.48) | MAOAMAOBDPP4RIPK1DPP7 | |
| SCHEMBL14355719 | 0.82 | DPP4 (0.48) | MAOAMAOBDPP4RIPK1DPP7 | |
| SCHEMBL12104028 | 0.82 | DPP4 (0.48) | MAOAMAOBDPP4RIPK1DPP7 | |
| SCHEMBL7712951 | 0.81 | MAOA (0.42) | KDM6BMAOAMAOBDPP4RIPK1 | |
| SCHEMBL7712985 | 0.81 | MAOA (0.42) | KDM6BMAOAMAOBDPP4RIPK1 | |
| SCHEMBL5807390 | 0.79 | TRPA1 (0.48) | KDM6BMAOBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |