Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991954 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL7711654 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7708368 | 0.84 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL7708492 | 0.83 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7983784 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL7705039 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7713493 | 0.77 | MEN1 (0.52) | ALDH1A1MEN1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL7711332 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7711544 | 0.75 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7705073 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358515-B2 | ANTIHYPERTENSIVE PHARMACEUTICAL COMPOSITION; TREATMENT OF GLAUCOMA | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | claimed |