Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.52 |
| ▸ | KDM6B | O15054 | 2/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28909832 | 0.87 | KDM4C (0.50) | KDM4CKDM6BHCAR3CISD1CYP2C9 | |
| SCHEMBL6413980 | 0.81 | KDM6B (0.46) | KDM4CKDM6BHCAR3CISD1CYP2C9 | |
| Hydrochloric Acid SCHEMBL9132968 | 0.80 | KDM6B (0.53) | KDM4CKDM6BHCAR3CISD1CYP2C9 | |
| SCHEMBL11252644 | 0.76 | PLK1 (0.47) | KDM4CKDM6BHCAR3CISD1CNR1 | |
| SCHEMBL29033346 | 0.75 | KDM6B (0.57) | KDM4CKDM6BHCAR3CISD1CYP2C9 | |
| SCHEMBL5889262 | 0.74 | GRM2 (0.44) | CYP2C9 | |
| SCHEMBL29634002 | 0.72 | PPARA (0.47) | PLK1 | |
| SCHEMBL9903584 | 0.72 | PPARA (0.47) | PLK1 | |
| SCHEMBL28912518 | 0.71 | KDM6B (0.57) | KDM4CKDM6BHCAR3CISD1CYP2C9 | |
| SCHEMBL16114874 | 0.71 | ABCB11 (0.46) | KDM4CKDM6BHCAR3CISD1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358231-B1 | Transdermal anesthetizing solution and method and apparatus for anesthetizing the ear canal and tympanic membrane | BIOPOLYMER, INC. | 2002-03-19 | — | — | US | disclosed |