Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708520 | 0.81 | KDM4C (0.52) | KDM6BKDM4CHCAR3CNR1CISD1 | |
| SCHEMBL11252644 | 0.78 | PLK1 (0.47) | KDM6BKDM4CHCAR3CNR1CISD1 | |
| Hydrochloric Acid SCHEMBL28909832 | 0.76 | KDM4C (0.50) | KDM6BKDM4CHCAR3CNR1CISD1 | |
| SCHEMBL15774412 | 0.75 | NCF1 (0.39) | KDM6BKDM4CHRH3KDM4EHPGD | |
| SCHEMBL9481778 | 0.74 | TAAR1 (0.43) | CYP1A2DRD4ACHEHTR2AHTR2C | |
| SCHEMBL1894574 | 0.73 | LMNA (0.49) | KDM6BKDM4CHCAR3LMNACNR1 | |
| SCHEMBL29033346 | 0.72 | KDM6B (0.57) | KDM6BKDM4CHCAR3CNR1CISD1 | |
| SCHEMBL9242441 | 0.71 | CA12 (0.41) | KDM6BKDM4CLMNACNR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9124351 | 0.70 | LMNA (0.42) | KDM6BKDM4CLMNACNR1CYP1A2 | |
| SCHEMBL294836 | 0.69 | CYP1A2 (0.50) | CYP1A2KDM4ERAB9AHPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014823-A1 | Topical anesthetic composition and method of administration | HAWKINS CHEMICAL, INC. | 2005-01-20 | — | — | US | disclosed |