Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | TK2 | O00142 | 11/20 | 0.42 |
| ▸ | TK1 | P04183 | 7/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702799 | 0.90 | TYMP (0.54) | TYMPTK2TK1 | |
| SCHEMBL7702801 | 0.90 | TYMP (0.54) | TYMPTK2TK1 | |
| SCHEMBL22984025 | 0.90 | TYMP (0.54) | TYMPTK2TK1 | |
| SCHEMBL16566911 | 0.88 | TYMP (0.54) | TYMPTK2TK1 | |
| SCHEMBL16566912 | 0.88 | TYMP (0.54) | TYMPTK2TK1 | |
| SCHEMBL16401541 | 0.88 | TYMP (0.54) | TYMPTK2TK1 | |
| SCHEMBL16401538 | 0.88 | TYMP (0.54) | TYMPTK2TK1 | |
| SCHEMBL2577261 | 0.88 | TK2 (0.46) | TK2TK1HSP90AA1 | |
| SCHEMBL3069438 | 0.85 | TYMP (0.62) | TYMPTK2TK1 | |
| SCHEMBL9710318 | 0.85 | TYMP (0.62) | TYMPTK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359124-B1 | NUCLEOTIDE SEQUENCES FOR USE IN THE DIAGNOSIS, DETECTION AND TREATMENT OF ARRHYTHMIA, LONG Q-T SYNDROME AND CANCERS | ISIS PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | disclosed |
| US-5965722-A | OLIGONUCLEOTIDE WITH METHYLENE(METHYLIMINO) LINKAGES ALTERNATING WITH PHOSPHOROTHIOATE OR PHOSPHODIESTER LINKAGES; WITH INCREASED NUCLEASE RESISTANCE, STABILITY, AFFINITY FOR MESSENGER RNA; ANTICARCINOGENIC/ANTIARRHYTHMIA AGENTS | ISIS PHARMACEUTICALS, INC. (US) | 1999-10-12 | — | — | US | disclosed |