Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980903 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1MAPTALOX5GAA | |
| 1,4-Butanediol SCHEMBL9285180 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1MAPTALOX5GAA | |
| SCHEMBL10987134 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1MAPTALOX5GAA | |
| 1,6-Hexanediol SCHEMBL9278879 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1MAPTALOX5GAA | |
| SCHEMBL2989121 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1MAPTALOX5GAA | |
| SCHEMBL35629 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1MAPTALOX5GAA | |
| SCHEMBL29366321 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1MAPTALOX5GAA | |
| Ethylene Glycol SCHEMBL949668 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1MAPTALOX5GAA | |
| SCHEMBL28929217 | 0.77 | CA2 (0.38) | KDM4EALDH1A1MAPTPOLBCA2 | |
| SCHEMBL22899869 | 0.77 | CA2 (0.35) | KDM4EALDH1A1MAPTALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359101-B1 | POLYMERIZING AN EPOXIDE IN THE PRESENCE OF A DOUBLE METAL CYANIDE CATALYST AND A FIRST STARTER, REACTING WITH EPOXIDE TO PRODUCE POLYETHERPOLYOL | SYNUTHANE INTERNATIONAL, INC. | 2002-03-19 | — | — | US | claimed |
| US-6359101-B1 | POLYMERIZING AN EPOXIDE IN THE PRESENCE OF A DOUBLE METAL CYANIDE CATALYST AND A FIRST STARTER, REACTING WITH EPOXIDE TO PRODUCE POLYETHERPOLYOL | SYNUTHANE INTERNATIONAL, INC. | 2002-03-19 | — | — | US | disclosed |