Ethylene Glycol

Ethylene Glycol

SCHEMBL949668

OCCO.OCCc1c(O)ccc(O)c1CCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPT P10636 4/20 0.48
GAA P10253 2/20 0.48
ALOX5 P09917 1/20 0.48
BACE1 P56817 1/20 0.48
CA2 P00918 3/20 0.42
TDP1 Q9NUW8 3/20 0.38
HSD17B10 Q99714 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALOX15 P16050 2/20 0.33
CA1 P00915 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
IGF1R P08069 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366321 0.97 KDM4E (0.50) KDM4EALDH1A1MAPTGAAALOX5
SCHEMBL35629 0.97 KDM4E (0.50) KDM4EALDH1A1MAPTGAAALOX5
1,4-Butanediol SCHEMBL9285180 0.89 KDM4E (0.44) KDM4EALDH1A1MAPTGAAALOX5
1,6-Hexanediol SCHEMBL9278879 0.87 KDM4E (0.43) KDM4EALDH1A1MAPTGAAALOX5
SCHEMBL10987134 0.87 KDM4E (0.43) KDM4EALDH1A1MAPTGAAALOX5
SCHEMBL2982538 0.83 ALDH1A1 (0.44) KDM4EALDH1A1MAPTGAAALOX5
SCHEMBL9404118 0.83 IDO1 (0.41) KDM4EALDH1A1MAPTGAAALOX5
Phenol SCHEMBL3060947 0.83 TDP1 (0.50) KDM4EALDH1A1MAPTGAAALOX5
Ether SCHEMBL9745518 0.81 ALDH1A1 (0.39) KDM4EALDH1A1MAPTGAAALOX5
SCHEMBL7708587 0.80 KDM4E (0.41) KDM4EALDH1A1MAPTGAAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9878487-B2 Multi-shape product SYRACUSE UNIVERSITY (US) 2018-01-30 US disclosed
US-9533469-B2 Self-healing product SYRACUSE UNIVERSITY (US) 2017-01-03 US disclosed
WO-2011109619-A2 MULTI-SHAPE PRODUCT SYRACUSE UNIVERSITY (US) 2011-09-09 WO disclosed
US-20110217547-A1 MULTI-SHAPE PRODUCT SYRACUSE UNIVERSITY (US) 2011-09-08 US disclosed
US-20110003159-A1 SELF-HEALING PRODUCT UNITED STATES DEPARTMENT OF ENERGY 2011-01-06 US disclosed
WO-2010075508-A1 SELF-HEALING PRODUCT SYRACUSE UNIVERSITY (US) 2010-07-01 WO disclosed