SCHEMBL7708640

SCHEMBL7708640

CC(C)(C)Oc1ccc(-c2[c]cccc2-c2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.35
PPARA Q07869 3/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
PPARD Q03181 1/20 0.35
RIPK1 Q13546 1/20 0.35
ABL1 P00519 1/20 0.32
ABCB1 P08183 1/20 0.32
BCR P11274 1/20 0.32
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1867724 0.81 ABL1 (0.50) ABL1ABCB1BCR
SCHEMBL6573031 0.80 FFAR4 (0.40) KIF11
SCHEMBL7708791 0.78 ELANE (0.50) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL7702905 0.77 KIF11 (0.38) KIF11
SCHEMBL8571095 0.77 ABL1 (0.50) ABL1ABCB1BCR
SCHEMBL7703864 0.75 GSTP1 (0.49)
SCHEMBL8858259 0.74 PPARG (0.47) PPARGPPARACYP2C9CYP2C19PPARD
SCHEMBL7705609 0.74 MEN1 (0.33)
SCHEMBL7711372 0.74 CA12 (0.47)
SCHEMBL8529551 0.73 KIF11 (0.38) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed
US-5612170-A SILICONE, PHOTO ACID GENERATOR, DISSOLUTION INHIBITOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-03-18 US disclosed