SCHEMBL7708643

SCHEMBL7708643

Cc1cc2c(C)ccc(C)c2c(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.39
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
CYP2A6 P11509 2/20 0.33
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8889111 0.83 CYP1A2 (0.43) CYP1A2TSHRALDH1A1CYP3A4HPGD
SCHEMBL30674801 0.76 CYP1A2 (0.53) CYP1A2TSHRALDH1A1CYP3A4HPGD
SCHEMBL601246 0.76 CYP1A2 (0.53) CYP1A2TSHRALDH1A1CYP3A4HPGD
SCHEMBL31001023 0.73 CYP1A2 (0.56) CYP1A2TSHRALDH1A1CYP3A4HPGD
SCHEMBL5250464 0.72 TSHR (0.48) CYP1A2TSHRALDH1A1CYP3A4HPGD
SCHEMBL5399249 0.72 ADORA3 (0.32) ADORA3
SCHEMBL19011753 0.69 ACHE (0.39) CYP1A2ALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL598994 0.68 CYP1A2 (0.39) CYP1A2TSHRALDH1A1CYP3A4HPGD
SCHEMBL4078654 0.67 TSHR (0.38) CYP1A2TSHRALDH1A1CYP3A4TDP1
SCHEMBL10434554 0.67 CYP1A2 (0.58) CYP1A2TSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6365762-B1 IN THE PRESENCE OF A RHENIUM CONTAINING CATALYST AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 2002-04-02 US disclosed
EP-0665209-B1 Process for the catalytic oxidation of aromatic compounds HOECHST AG (DE) 1998-12-02 EP disclosed
US-5710292-A RHENIUM CATALYSTS HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
EP-0686618-B1 Process for the selective oxidation of aromatic compounds HOECHST AG (DE) 1998-01-14 EP disclosed
US-5616734-A OXIDIZING AROMATIC RING OF ELECTRON-RICH COMPOUNDS IN PRESENCE OF OXYGEN-CONTAINING ORGANIC RHENIUM CATALYST AND PEROXIDE-CONTAINING COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-01 US disclosed
EP-0686618-A1 Process for the selective oxidation of aromatic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-13 EP disclosed
EP-0665209-A1 Process for the catalytic oxidation of aromatic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-02 EP disclosed