Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800042 | 0.86 | CA12 (0.50) | GABRG2GABRB3GABRA5GABRA3CA12 | |
| SCHEMBL6642630 | 0.83 | TSHR (0.53) | CA12CA1CA2CA9TSHR | |
| SCHEMBL7392508 | 0.82 | GPR17 (0.47) | GABRG2GABRB3GABRA5GABRA3CA12 | |
| SCHEMBL1510035 | 0.81 | KMO (0.59) | CA12CA1CA2CA9TSHR | |
| SCHEMBL67941 | 0.80 | CA12 (0.68) | GABRG2GABRB3GABRA5GABRA3CA12 | |
| SCHEMBL7468586 | 0.80 | PARP1 (0.46) | TSHRERN1RAB9ACDK8PDK2 | |
| SCHEMBL1221576 | 0.79 | TSHR (0.67) | GABRG2GABRB3GABRA5GABRA3CA12 | |
| SCHEMBL29410906 | 0.79 | TSHR (0.67) | GABRG2GABRB3GABRA5GABRA3CA12 | |
| SCHEMBL27715902 | 0.78 | CA12 (0.71) | GABRG2GABRB3GABRA5GABRA3CA12 | |
| SCHEMBL4287323 | 0.78 | TSHR (0.52) | GABRG2GABRB3GABRA5GABRA3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |