Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475208 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL173883 | 0.80 | CYP1A2 (0.51) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL30080837 | 0.80 | CYP1A2 (0.51) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL6628038 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL6632235 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL6476439 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL28246708 | 0.78 | LTB4R (0.50) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL3367528 | 0.78 | TAAR1 (0.50) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL5144294 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KEAP1NPC1RAB9APOLB | |
| SCHEMBL29223826 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KEAP1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |