Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245884 | 1.00 | CYP19A1 (0.47) | CYP19A1TBXAS1POLBALPIALPG | |
| SCHEMBL7245883 | 1.00 | CYP19A1 (0.47) | CYP19A1TBXAS1POLBALPIALPG | |
| SCHEMBL7241801 | 0.88 | CYP19A1 (0.52) | CYP19A1TBXAS1POLB | |
| SCHEMBL7241803 | 0.88 | CYP19A1 (0.52) | CYP19A1TBXAS1POLB | |
| SCHEMBL7708954 | 0.88 | CYP19A1 (0.52) | CYP19A1TBXAS1POLB | |
| SCHEMBL7240901 | 0.88 | TBXAS1 (0.55) | CYP19A1TBXAS1POLB | |
| SCHEMBL7240899 | 0.88 | TBXAS1 (0.55) | CYP19A1TBXAS1POLB | |
| SCHEMBL7703357 | 0.82 | AGTR2 (0.48) | CYP19A1POLB | |
| SCHEMBL7703354 | 0.82 | AGTR2 (0.48) | CYP19A1POLB | |
| SCHEMBL8228722 | 0.81 | CYP19A1 (0.45) | CYP19A1TBXAS1POLBALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |