Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877407 | 0.92 | MAPT (0.57) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL7075294 | 0.88 | TSHR (0.57) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL7072045 | 0.88 | TSHR (0.50) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL5353531 | 0.86 | TSHR (0.65) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| Methyl Salicylate SCHEMBL4573550 | 0.86 | LMNA (0.54) | TSHRL3MBTL1TDP1ALDH1A1ABCB1 | |
| SCHEMBL28748376 | 0.85 | TSHR (0.53) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10459135 | 0.85 | TSHR (0.61) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL9969538 | 0.84 | TSHR (0.65) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6042513 | 0.84 | TSHR (0.59) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL11588678 | 0.84 | TSHR (0.59) | TSHRTBXAS1L3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |