Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339281 | 0.94 | LMNA (0.68) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL8982913 | 0.94 | LMNA (0.68) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL28679533 | 0.93 | ALDH1A1 (0.57) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL28932316 | 0.93 | ALDH1A1 (0.57) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL975212 | 0.92 | TSHR (0.77) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL9969538 | 0.92 | TSHR (0.65) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL975209 | 0.90 | TSHR (0.75) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL976078 | 0.90 | TSHR (0.75) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28026710 | 0.90 | TSHR (0.62) | TSHRL3MBTL1TDP1LMNACYP3A4 | |
| SCHEMBL974445 | 0.90 | TSHR (0.75) | TSHRL3MBTL1TDP1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566522-B | Catalytic component and its catalyst for ethylene polymerization | 中国石油化工股份有限公司 | 2018-01-23 | — | — | CN | claimed |
| CN-105566524-B | A kind of catalytic component and its catalyst for ethylene polymerization | 中国石油化工股份有限公司 | 2018-01-23 | — | — | CN | claimed |
| CN-105482003-B | Carrier and its catalyst used in a kind of ethylene rolymerization catalyst | 中国石油化工股份有限公司 | 2018-01-23 | — | — | CN | claimed |
| US-4487845-A | COORDINATION, POLYMERIZATION CATALYST FOR OLEFINS | STAUFFER CHEMICAL COMPANY (US) | 1984-12-11 | — | — | US | claimed |
| CN-117924556-A | Spherical magnesium halide adduct and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924555-A | Catalyst component, catalyst system, application of catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113249037-B | Photocurable adhesive composition for optical film, photocurable adhesive layer for optical film, optical element, and display device | 三星SDI株式会社 | 2024-03-01 | — | — | CN | disclosed |
| CN-113249037-A | Photocurable adhesive composition for optical film, photocurable adhesive layer for optical film, optical member and display device | 三星SDI株式会社 | 2021-08-13 | — | — | CN | disclosed |
| CN-105622423-B | A kind of adduct of magnesium halides and its preparation method and application | 中国石油化工股份有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-105622793-B | For the catalytic component and catalyst system of olefinic polymerization and its application and olefine polymerizing process | 中国石油化工股份有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-105541877-B | Adduct of magnesium halides and application and the catalytic component for olefinic polymerization and catalyst system and application and olefine polymerizing process | 中国石油化工股份有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-105622644-B | A kind of adduct of magnesium halides and its application | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | disclosed |
| US-8470985-B2 | Triazole compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| CN-102796210-A | Catalyst component and catalyst system for olefin polymerization, application of catalyst component and catalyst system, and olefin polymerization method | CHINA PETROLEUM & CHEMICAL | 2012-11-28 | — | — | CN | disclosed |
| CN-102796127-A | Spherical magnesium halide adduct and preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2012-11-28 | — | — | CN | disclosed |
| US-20120252747-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2012-10-04 | — | — | US | disclosed |
| US-8202843-B2 | Macrocyclic compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20080045585-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2008-02-21 | — | — | US | disclosed |
| US-7297472-B2 | Processing method for photoresist master, production method for recording medium-use mater, production method for recording medium, photoresist master, recording medium-use master and recording medium | TDK CORPORATION (JP) | 2007-11-20 | — | — | US | disclosed |
| US-4487845-A | COORDINATION, POLYMERIZATION CATALYST FOR OLEFINS | STAUFFER CHEMICAL COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252747-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CCNO, PTGDR, CCNE1 | TSHR 762/4885L3MBTL1 3302/4885TDP1 2776/4885 |
| US-20080045585-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | VIP, PROKR1, PGC | TSHR 3269/4885L3MBTL1 3458/4885TDP1 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.