Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 13/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714808 | 0.95 | GPR183 (0.35) | GPR84GPR183CCR5KDM1ACYP19A1 | |
| SCHEMBL7759563 | 0.92 | CXCR5 (0.32) | GPR84GPR183CCR5KDM1AHTT | |
| SCHEMBL7714852 | 0.87 | CXCR5 (0.33) | GPR183CCR5SMN1; SMN2 | |
| SCHEMBL29001777 | 0.79 | KDM1A (0.40) | GPR84CCR5KDM1AMAOAMAOB | |
| SCHEMBL7714533 | 0.77 | LMNA (0.30) | SMN1; SMN2 | |
| SCHEMBL7714823 | 0.77 | CYP19A1 (0.33) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15821065 | 0.77 | HDAC6 (0.44) | GPR84CCR5KDM1ASMN1; SMN2MAOA | |
| SCHEMBL7714890 | 0.77 | CYP19A1 (0.34) | KDM1ACYP19A1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL18599627 | 0.75 | GAA (0.43) | GPR84CCR5KDM1ASMN1; SMN2MAOA | |
| SCHEMBL7708911 | 0.75 | GRM7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |