Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 6/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.31 |
| ▸ | RELA | Q04206 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714852 | 0.95 | CXCR5 (0.33) | CXCR5CXCR3GPR183SMN1; SMN2NPC1 | |
| SCHEMBL7709008 | 0.92 | GPR84 (0.36) | GPR183SMN1; SMN2GPR84CCR5HTT | |
| SCHEMBL7714808 | 0.87 | GPR183 (0.35) | GPR183GPR84CCR5KDM1AALDH1A1 | |
| SCHEMBL7714502 | 0.78 | PNMT (0.34) | CXCR5CXCR3NPC1RAB9ACCR5 | |
| SCHEMBL7712837 | 0.77 | MEN1 (0.36) | CXCR5CXCR3NPC1RAB9AMAPT | |
| SCHEMBL7712650 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL7714823 | 0.75 | CYP19A1 (0.33) | — | |
| SCHEMBL7714533 | 0.75 | LMNA (0.30) | SMN1; SMN2LMNA | |
| SCHEMBL7759560 | 0.75 | NOTUM (0.33) | CXCR5CXCR3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7714890 | 0.74 | CYP19A1 (0.34) | SMN1; SMN2NPC1RAB9AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |