Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PLK1 | P53350 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16107212 | 0.90 | PLK1 (0.36) | TLR8CNR1CNR2LMNAPLK1 | |
| SCHEMBL10253638 | 0.88 | CNR1 (0.36) | TLR8NPC1CNR1CNR2TP53 | |
| SCHEMBL1068828 | 0.88 | TLR8 (0.35) | TLR8NPC1CNR1CNR2TP53 | |
| SCHEMBL30575191 | 0.87 | CNR1 (0.34) | TLR8NPC1CNR1CNR2TP53 | |
| SCHEMBL13366375 | 0.85 | NPC1 (0.39) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL26629793 | 0.85 | ALDH2 (0.47) | SMN1; SMN2PLK1ALDH2 | |
| SCHEMBL8387404 | 0.84 | NR5A1 (0.39) | CNR2TP53TSHR | |
| SCHEMBL15854557 | 0.84 | LMNA (0.36) | TLR8NPC1TP53POLBNFKB1 | |
| SCHEMBL5081652 | 0.84 | CNR2 (0.32) | TLR8NPC1CNR1CNR2TP53 | |
| SCHEMBL14480246 | 0.84 | PLA2G4B (0.39) | TLR8NPC1CNR1CNR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355708-B2 | USEFUL IN STABILIZING POLYMERS AND OTHER MATERIALS FROM DEGRADATION BY ENVIRONMENTAL FORCES SUCH AS ACTINIC RADIATION (ULTRAVIOLET LIGHT), OXIDATION, MOISTURE, ATMOSPHERIC POLLUTANTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| US-20010031866-A1 | Novel trisaryl-1,3,5-triazine ultraviolet light absorbers | GUPTA RAM BABOO (US) | 2001-10-18 | — | — | US | disclosed |
| US-6242597-B1 | STABILIZERS WITH A BONDABLE GROUP HAVING AN ACTIVE (ACIDIC) HYDROGEN; MIGRATION BETWEEN POLYMER LAYERS IS REDUCED | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-06-05 | — | — | US | disclosed |
| EP-1032563-A1 | TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999026934-A1 | TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031866-A1 | Novel trisaryl-1,3,5-triazine ultraviolet light absorbers | ERCC5, XRCC5, ERCC1 | TLR8 3657/4885NPC1 2328/4885CNR1 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.