SCHEMBL7709568

SCHEMBL7709568

Cc1cc(S(=O)(=O)O)cc(N)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.47
ALDH1A1 P00352 5/20 0.47
HSD17B10 Q99714 3/20 0.47
CASP6 P55212 3/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
GAA P10253 4/20 0.44
NSD2 O96028 2/20 0.44
PLCG1 P19174 1/20 0.44
DNMT1 P26358 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 1/20 0.41
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPT P10636 3/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5499800 0.98 NT5E (0.46) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL4812412 0.89 ALDH1A1 (0.52) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL11331642 0.87 ALDH1A1 (0.50) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL84322 0.84 LCK (0.44) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL21589353 0.83 NT5E (0.47) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL9336949 0.83 ALDH1A1 (0.54) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL17262954 0.82 ALDH1A1 (0.60) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL9337500 0.82 ALDH1A1 (0.49) NT5EALDH1A1HSD17B10CASP6CYP2C9
SCHEMBL2437905 0.81 G6PD (0.41) GAAL3MBTL1TSHRTDP1MAPT
SCHEMBL28316697 0.81 CA1 (0.45) ALDH1A1HSD17B10CYP2C9CYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361919-B1 PHOTOSENSITIVE MATERIAL KONICA CORPORATION (JP) 2002-03-26 US disclosed
EP-1011015-A1 Silver halide photographic light sensitive material and hydrazine compound employed in it KONICA CORPORATION (JP) 2000-06-21 EP disclosed
US-4754023-A Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member CIBA-GEIGY CORPORATION (US) 1988-06-28 US disclosed