Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702182 | 0.79 | TACR1 (0.60) | TACR1 | |
| SCHEMBL7704059 | 0.78 | TACR1 (0.51) | TACR1 | |
| SCHEMBL7707100 | 0.78 | TACR1 (0.64) | TACR1 | |
| SCHEMBL5966366 | 0.78 | TACR1 (0.81) | TACR1 | |
| SCHEMBL5780710 | 0.77 | TACR1 (0.69) | TACR1 | |
| SCHEMBL5779622 | 0.75 | TACR1 (0.75) | TACR1 | |
| SCHEMBL6016592 | 0.74 | NPC1 (0.45) | — | |
| SCHEMBL5782663 | 0.74 | TACR1 (0.72) | TACR1 | |
| SCHEMBL6016333 | 0.73 | TACR1 (0.56) | TACR1 | |
| SCHEMBL5779692 | 0.73 | TACR1 (0.73) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000073279-A1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-07 | — | — | WO | disclosed |