Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.80 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.61 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108112 | 0.90 | CA1 (0.72) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL16417857 | 0.82 | CA1 (0.69) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL7709781 | 0.81 | MEN1 (0.56) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL7563980 | 0.81 | MEN1 (0.55) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL109158 | 0.80 | MAPT (0.73) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL107219 | 0.79 | MAPT (0.71) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL109104 | 0.79 | MAPT (0.68) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL2266963 | 0.79 | MAPT (0.68) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL17899787 | 0.78 | CA1 (0.69) | MEN1KMT2AGAAERCC1ERCC4 | |
| SCHEMBL22773358 | 0.78 | CA1 (0.69) | MEN1KMT2AGAAERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |